NOTICE: Due to the COVID-19 situation, the THREB office will temporarily become a virtual office only. The Administrative Coordinator and the Chair will be working from home and meetings will be by teleconference. Telephone messages will be checked and responded to on Mondays and Wednesdays. For the duration of this situation, please submit all applications, other materials and queries electronically only. No hard copies will be required for now. Please email all queries and materials to the Administrative Coordinator with a copy to the Chair

The Tri-Hospital Research Ethics Board (THREB) provides ethical oversight for all research activities that involve human participants, their data and/or biological materials, conducted under the auspices of Cambridge Memorial Hospital, Grand River Hospital and St. Mary's General Hospital. All research conducted within or on behalf of the Tri-hospitals must be approved by THREB before research may begin, with the exception of research reviewed by an alternate Board of Record (e.g. the Ontario Cancer Research Ethics Board).

Conducting Research at one or more of the Tri-Hospitals:

Prior to the ethics review of a submission by THREB, all new studies must undergo an administrative review at the hospital(s) where the study will be conducted. Please submit the complete application package to the applicable hospital research representative for administrative review. Once a submission has received administrative approval, it will be forwarded to THREB.

Please refer to the Submission Checklist for new submission requirements

Each hospital has its own schedule for reviewing new studies. Please consult the applicable hospital research representative for their dates and deadlines.

Cambridge Memorial HospitalGrand River HospitalSt. Mary's General Hospital
Stephanie Pearsall Vice President Clinical Programs
700 Coronation Boulevard, Cambridge, Ontario N1R 3G2 Telephone: 519-621-2333 extension 2456
Sarah Laferriere Manager Research & Clinical Trials
835 King Street West, Kitchener, Ontario, N2G 1G3 Telephone: 519-749-4300 extension 2876
Nicole Johnson, Interim Vice President, Quality, People & Performance
911 Queen’s Blvd. Kitchener, Ontario N2M 1B2
Telephone: 519-749-6578 extension 6403

THREB Meeting Dates:

  • THREB meets the first Wednesday of every month from 12-1:30 pm. For studies requiring a full board review, a completed application package must be received by the second Wednesday of the month prior to the meeting date. Please plan sufficient time for your study to undergo Administrative and THREB review.
  • All other submissions (amendments, annual renewals, protocol deviations, study closures, etc) will be reviewed in order of receipt.
  • These submissions should be sent to the THREB Administrative Assistant, Shelley Croth, at

Co-ordinated ethics review process between THREB and University of Waterloo:

University of Waterloo students wishing to conduct research at any of the Tri-hospitals must undergo a co-ordinated ethics review process. Full details can be found here.


THREB requires electronic submission of materials. To provide sufficient time for review, completed application packages and other items for review must be received by the second Wednesday of the month prior to the THREB meeting date. Please email an electronic copy of the submission to

Application forms

Forms for continuing review

More information is available under the following links:

For more information, or to send an application and other forms, contact:

Shelley Croth, THREB Administrative Coordinator

Tri-Hospital Research Ethics Board

Grand River Hospital, Building - Forty Green, room K415,

835 King Street West, Kitchener, ON N2G 1G3

Phone: 519-749-4300, extension 5367 Fax: 519-749-4282


The THREB office is open Monday and Wednesday only.

You can reach the THREB Chairperson, Alison Williams at: